In 1-gallon resealable food-storage plastic bag, place beef, flour, salt and pepper; seal bag. Shake to coat beef evenly.
In 12-inch nonstick skillet, heat 1 tablespoon of the oil over medium-high heat. Add half of the beef; cook 4 to 5 minutes, turning once, until browned on all sides. Repeat with remaining oil and beef.
Spray 3 1/2- to 4-quart slow cooker with cooking spray. In cooker, place onion, carrots and celery; place beef on top. In medium bowl, mix broth, wine, tomato sauce and garlic. Pour over beef.
Cover; cook on Low heat setting 7 to 9 hours.