Spray 4-quart slow cooker with cooking spray. Sprinkle beef with 1/2 teaspoon of the pepper and the salt. In 4-quart Dutch oven, heat oil over medium-high heat. Cook beef in oil until brown on all sides. Place beef in slow cooker.
In small bowl, mix salsa, cumin, chili powder and remaining 1/2 teaspoon pepper. Pour over beef.
Cover; cook on Low heat setting 10 hours or until beef is very tender.