Heat oven to 400°F. In 10-inch skillet, cook beef over medium-high heat 5 to 7 minutes, stirring occasionally, until thoroughly cooked; drain. Lightly spray large cookie sheet with cooking spray. Unroll dough on work surface. Cut dough into 4 equal pieces; place on cookie sheet. Press out each piece of dough to form 6x5-inch rectangle. With fingers, create slight rim on edge of each dough rectangle. Bake 8 minutes.
Spread about 2 tablespoons pizza sauce just to rim of each crust; sprinkle with oregano. Top with pepperoni, beef and cheeses.
Bake 8 to 10 minutes until cheese in center is melted.