Heat oven to 350°F. Cook and drain pasta as directed on package.
Mix pasta, chicken, Alfredo pasta sauce and spinach. Separate dough into 8 biscuits; press each biscuit to 5 1/2-inch round. Firmly press 1 biscuit in bottom and up side of each of 8 ungreased jumbo muffin cups, forming 1/4-inch rim. Fill with chicken mixture; sprinkle with cheese.
Bake 28 to 32 minutes or until golden brown. Cool 1 minute; remove from pan.